在不良反应方面,心动过缓与低血压常同时发生,给予麻黄素10mg-30mg治疗后,血压回升,心率恢复。罗哌卡因组低血压和心动过缓的发生率与布比卡因组相似,但罗哌卡因组恶心呕吐的发生率随局麻药剂量增加而升高;各组均未发现术后头痛,可能是采用了笔尖型带侧孔腰麻穿刺针,此类穿刺针与传统的锐头穿刺针相比,穿刺时是钝性分开,而后者是切断硬膜纤维,故减少了腰麻后的头痛发生率[8]。 在腰-硬联合麻醉下行剖宫产术,12mg、15mg罗哌卡因与10mg布比卡因的麻醉效能相似;罗哌卡因腰麻下感觉阻滞起效时间和扩散范围不受局麻药用量影响。
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